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Posts tagged with:  senolytics

Are The Natural Senolytic Compounds in Food Enough to Experience Senolytic Benefits?

By: The Posts Author | Posted on: 28 Dec 23

Cellular senescence is a physiological process through which, in response to stress, cells stop dividing but don’t die. Some senescent cells linger indefinitely in tissues by upregulating pro-survival mechanisms called senescent cell anti-apoptotic pathways (SCAPs) and downregulating pro-apoptotic pathways [1–3]. Accumulation of lingering senescent cells occurs with aging and can impair tissue function [4]. This connection to unhealthy aging occurs in part because senescent cells produce chemical mediators, collectively known as senescence-associated secretory profile (SASP), that may disrupt tissue function and immune responses and affect health [5,6].Maintaining balanced senescence is important because, although senescent cells can have undesirable actions, cellular senescence

Cellular senescence is a physiological process through which, in response to stress, cells stop dividing but don’t die. Some senescent cells linger indefinitely in tissues by upregulating pro-survival mechanisms called senescent cell anti-apoptotic pathways (SCAPs) and downregulating pro-apoptotic pathways [1–3]. Accumulation of lingering senescent cells occurs with aging and can impair tissue function [4]. This connection to unhealthy aging occurs

Longevity Ingredient Spotlight: Fisetin Benefits

By: The Posts Author | Posted on: 10 Nov 23

Cellular senescence is one of the twelve Hallmarks of Aging [1]; it is a characteristic of getting older in most organisms (including humans). Fisetin is one of a small group of compounds called senolytics that researchers are studying for countering cellular senescence.Senescence is a cellular stress response characterized by a permanent state of growth arrest (i.e., cells stop dividing but don’t die) and the production of chemical mediators that influence tissue health. With aging, senescent cells can linger in tissues and gradually accumulate, promoting tissue dysfunction, unhealthy aging, and age-related health decline [2,3].Senescent cells can be selectively eliminated with senolytics. Senolytics

Cellular senescence is one of the twelve Hallmarks of Aging [1]; it is a characteristic of getting older in most organisms (including humans). Fisetin is one of a small group of compounds called senolytics that researchers are studying for countering cellular senescence.Senescence is a cellular stress response characterized by a permanent state of growth arrest (i.e., cells stop dividing but

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