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Are The Natural Senolytic Compounds in Food Enough to Experience Senolytic Benefits?

By: The Posts Author | Posted on: 28 Dec 23

Cellular senescence is a physiological process through which, in response to stress, cells stop dividing but don’t die. Some senescent cells linger indefinitely in tissues by upregulating pro-survival mechanisms called senescent cell anti-apoptotic pathways (SCAPs) and downregulating pro-apoptotic pathways [1–3]. Accumulation of lingering senescent cells occurs with aging and can impair tissue function [4]. This connection to unhealthy aging occurs in part because senescent cells produce chemical mediators, collectively known as senescence-associated secretory profile (SASP), that may disrupt tissue function and immune responses and affect health [5,6].Maintaining balanced senescence is important because, although senescent cells can have undesirable actions, cellular senescence

Cellular senescence is a physiological process through which, in response to stress, cells stop dividing but don’t die. Some senescent cells linger indefinitely in tissues by upregulating pro-survival mechanisms called senescent cell anti-apoptotic pathways (SCAPs) and downregulating pro-apoptotic pathways [1–3]. Accumulation of lingering senescent cells occurs with aging and can impair tissue function [4]. This connection to unhealthy aging occurs

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